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An established fact or truth is something that has been shown to be definitely true.
That link is an established medical fact.
那种联系是被证实了的医学事实。
If you use established to describe something such as an organization, you mean that it is well known because it has existed for a long time.
These range from established companies to start-ups.
这些包括老牌公司和新兴公司。
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